The Encyclopedia Of Dna Elements - 2407 Words

The Encyclopedia of DNA Elements (ENCODE) is a project designed to compare and contrast the repertoire of RNAs produced by the human cells and cross verify with other methods like NGS. After a five year start-up since the beginning of the ENCODE project just 1% of the human genome has been observed and what was achieved was just the confirmation of the results of previous studies. RNA has functions of coding, regulation, decoding, and gene expression. RNA highlights the sequential output from genomes which gives the genetic information. They define the cells regulatory capabilities by their synthesis, translation, transport, processing, and modification. DNA, RNA and cellular proteins are the three most essential macromolecules responsible for the existence of life as we know it. This paper paves way for the generation of a catalogue that contains all the RNAs and their functions. The ENCODE project, which stands for Encyclopedia of DNA elements aims to catalogue and classify the RNA elements generated by human cells. This data acquisition is required to characterize and identify the functionalities that result due to the presence of the human genome sequence. The entire ENCODE project duration is divided into two phases: †¢ Phase I: (1-5 years): examined 1% of the human genome †¢ Phase II: (5-10 years): The interrogation of the complete human genome As per the findings of the ENCODE project, it is concluded that new RNAs consist of either of the two major cellularShow MoreRelatedThe Encyclopedia Of Dna Elements2709 Words   |  11 PagesINTRODUCTION The Encyclopedia of DNA Elements (ENCODE) is a project designed to compare and contrast the repertoire of RNAs produced by the human cells and cross verify with other methods like NGS. After a five year start-up since the beginning of the ENCODE project just 1% of the human genome has been observed and what was achieved was just the confirmation of the results of previous studies. RNA has functions of coding, regulation, decoding, and gene expression. RNA highlights the sequential outputRead MoreThe Human Genome Project And Encyclopedia Of Dna Elements2847 Words   |  12 Pagesour life as we know it must start at the basics with our own DNA. DNA is the building blocks for all life, so to understand life we must analyze the mechanism of genetics. Projects like the Human Genome project and Encyclopedia of DNA elements (ENCODE) analyzes DNA to give society an interpretation of what the building code is and means. Our genetic code holds coding and non-coding sequences, at first researchers focused solely on coding DNA for it carried the function and means to life. The other non-codingRead MoreThe Cumulative Prognosis Time Distribution For The Selected Signaling Pathways904 Words   |  4 Pagesprognosis time distribution for the selected signaling pathways are shown in Fig. 4. The later activation of the IL-10 pathway in the symptomatic subjects can be explain ed by the anti-inflammatory nature of IL-10 and†¦. Similarly, the fact that the DNA sensing pathway is quick to become anomalous is likely due to the initial detection of viral ssRNA by RIG-I (Pichlmair, et al., 2006). In fig. 5, we show further evidence of the pathway cascade, i.e., the fraction of the subjects that have k pathwaysRead MoreStructure And Structure Of Membrane Proteins Essay922 Words   |  4 Pagesforms of genetic information in bacteria DNA sequence stored, i.e. bacterial chromosome and plasmids. The following are the properties of a bacterial chromosome. †¢ Location: Within nucleoid region , not surrounded by nuclear envelope. †¢ Number: 1 chromosome each cell. †¢ Size: E.coli 4640 kbp. †¢ Component: Single, double-stranded circular DNA. Also includes RNA and its participation in DNA replication, transcription and gene expression of regulatory proteins. DNA does not interact with histone proteinsRead MoreGenome Decoding: A Review of Three Articles1724 Words   |  7 Pagessubject by describing the mechanism of the human DNA itself far more complex than originally thought. The third has taken a totally new perspective and approached DNA from the point of cancer. I find the third the most persuasive since He-suk (2012) approached the subject from the readers perspective. He realized that cancer is one of our largest concerns today. It remains an undefeated epidemic that arouses huge interest and concern. By approaching DNA from the perspective of cancer, He-suk (2012)Read MoreBiological Networks And The Biomedical And Genomic Fields962 Words   |  4 Pages there has been an exponential increase in the genomic and clinical data. Two of the largest and â€Å"de ep† biomedical and genomic big datasets produced by large consortia are ENCODE (Encyclopedia of DNA Elements) and TCGA (The Cancer Genome Atlas). The ENCODE project14, 15 was launched to identify all functional elements in the human genome - regions of transcription, transcription factor association, chromatin structure and histone modification. The ENCODE project has generated more than 6000 genomicRead MoreHow The Firm Strategy Affect The Emergence Of The Genomic Industry?1489 Words   |  6 Pagesthe genomic industry as a viable source of profit4. (See Figure 2) Through the advancement of DNA sequencing through â€Å"Next Generation Sequencing† platform, such as Illumina (Solexa) sequencing and Roche 454 sequencing, the genomic industry has been able to go from a viable concept to deploying profitable genomic companies. (See Figure 2) With the continuous development of the Encyclopedia Of DNA Elements (ENCODE), through HGP and National Human Genome Research Institute (NHGRI), companies have beenRead MoreEssay on The Human Genome Project1437 Words   |  6 PagesEmbedded deeply in our body is the complex biological story. The Human Genome Project is the exploration of this intricate yet crucial storyline. The Genome is a complete set of genes that make up an organism. Genes are made up of DNA (deoxynucleic acid) which subsequently is made up of long paired strands. These paired strands attach in a specific manner, for example, Adenine (A) attaches itself to Thymine (T) and Cytosine(C) to Guanine (G). The genome is the perplexing key in instructing cellsRead Moreâ€Å"Challenges And Risks Of Genetically Engineered Organisms†.1655 Words   |  7 PagesUnited States for GMO crops. GMOs: Good or Bad for People and the Environment? The Hutchinson Unabridged Encyclopedia with Atlas and Weather Guide, edited by Helicon, 1st edition, 2016. Credo Reference. Accessed 04 Apr 2017. To find this encyclopedia article I used Credo Reference, using the search terms â€Å"GMOs and Health†. This article is found in The Hutchinson Unabridged Encyclopedia with Atlas and Weather Guide. The article gives a brief overview of what a GMO is and examples of how some foodsRead More`` Save The Animals : Stop Animal Testing `` By Lara Weber1241 Words   |  5 Pageshim to have neurological problems like body spasms and loud crying (Hawthorne). This is just one example of the many terrible experiments that are going on around the world. The next section talks about the similar DNA between humans and animals. Animals and humans share very similar DNA with each other. In the article â€Å"A Comparison of Human and Mouse Gene Co-expression Networks Reveals Conservation and Divergence at the Tissue, Pathway and Disease Levels† written by Gianni Monaco, Sipko Van Dam and